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Multi-Lipid Replenishing Moisturizer

Multi-Lipid Replenishing Moisturizer

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Regular price $110.00 USD
Regular price Sale price $110.00 USD

A rich, comprehensive formula featuring seven essential lipids and five hydrating agents. This moisturizer has been designed to help skin retain moisture to support the skin barrier health for a smoother, softer, and more plump appearance.

Size: 1.7 oz / 50 ml

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Minimizing wrinkles and a lifted appearance.

Designed to Improve skin’s

- Moisturization

- Softness

- Radiance

- Smoothness


- Dehydrated skin

- Rough texture

- Dullness

- Aging skin concerns


- Fast-absorbing

- Non-greasy

-Supports skin’s barrier function

-Leaves skin soft-to-touch

-Dermatologist tested

-No evidence in irritation

-Formulated without synthetic dyes, synthetic fragrances,

parabens, mineral oil

IDEAL FOR: those who want younger, healthier looking skin while reducing the look of wrinkles and lines.


Key Emollients

Ceramide 1
Ceramide 2
Ceramide 3
Ceramide 6
Linoleic Acid

Supporting Ingredients


Amino Acids


Hyaluronic Acid



All Ingredients

Purified Water, Cetearyl Alcohol, Glycerin, Caprylic/Capric Triglyceride, Cyclopentasiloxane, Sodium PCA, Dimethicone, Polysorbate 60, Ceramide AP, Ceramide EOP, Ceramide NP, Ceramide NG, Hexanoyl Dipeptide-3 Norleucine Acetate, Tetrapeptide-21, Superoxide Dismutase, Caffeine, Arginine, Ectoin, Cholesterol, Phytosphingosine, Bisabolol, Allantoin, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Tocopheryl Acetate, Linoleic Acid, Ascorbic Acid, Butyrospermum Parkii (Shea Butter) Extract, Oenothera Biennis (Evening Primrose) Oil, Sorbic Acid, Squalane, Lavandula Angustifolia (Lavender) Oil, Caprylyl Glycol, C13-14 Isoparaffin, Lecithin, Polyacrylamide, Cetearyl Glucoside, PEG-100 Stearate, Laureth-7, Glyceryl Stearate, Dimethicone Crosspolymer, Butylene Glycol, Carbomer, Xanthan Gum, Sodium Lauroyl Lactylate, Phenoxyethanol, Disodium EDTA.

Results Through Research.

Multi-Lipid Replenishing Moisturizer is clinically proven* to show statistically significant improvements in the appearance of skin radiance & pores , skin tone, texture, and more.


 improvement in skin texture & smoothness


 improvement in skin laxity/firmness


immediate improvement in hydration

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*Results based on a dermatologist-controlled, single-blinded 8-week clinical study of 36 subjects with twice daily application of Clinical Skin Multi-Lipid Replenishing Moisturizer. Criteria: Females ages 35-75 with moderate fine lines/wrinkles, uneven skin tone, skin dullness, skin roughness, lack of skin tone clarity, and lack of skin firmness. Average results shown.

Clinical Study Participants Reported ( after 8 weeks)

Substantial Results

97%* More elasticity and a softer feel

94%* Overall improvement in skin’s appearance

84%* Healthier looking skin

94%* Overall improvement in skin’s appearance

74%* Less visible fine lines and wrinkles

*Percentage of subjects who agree with the products results

Dermatologist Acclaimed

"The Clinical Skin's Multi-Lipid Replenishing Moisturizer is a ceramide-rich cream that provides luxurious hydration year-round. Its unique anti-aging formulation is well tolerated by even the most sensitive skin types. I love how it layers over my serums and provides a dewy appearance to my skin throughout the entire day."

Dr. Lisa R Ginn, M.D., F.A.A.D. Board Certified Dermatologist Fellowship-trained Cosmetic Laser Surgeon


"This rich yet lightweight moisturizer is the perfect final step to any skincare routine. Packed with the best ingredients for barrier strength and age-prevention, this product is a staple in any regimen that I recommend to every client, all skin types.

It is nourishing to dry and dehydrated skin, but not suffocating to those who are more oily or congested, and fragrance and irritant free to be comforting to sensitized skin. Finally, a luxury, quality skincare product that is inclusive to ALL!"

Megan Colwell, Licensed Esthetician

Customer Reviews

Based on 71 reviews
Elizabeth F.
Love love love

Not to heavy and soaks right into my skin and keeps it hydrated …I will be purchasing more

Lori Medina
Glowing Skin

The multi-lipid replenishing moisturizer is amazing my skin is glowing and looks hydrated without feeling sticky. I live in humid weather and clinical skin products works perfectly.

nancy luong
Perfect for all treatments type

This moisture is perfect when I am using retinal

Nettie Aguilar

Clinical Skin Multi-Lipid Replenishing Moisturizer

Clinical Skin Multi Lipid Replenishing Creme

I am motivated to write this review as this face Creme completely surprised me with its amazing benefits. I am a regular swimmer, have several autoimmune conditions, rosacea and in general deal with dehydrated and sometimes very dry skin. Recently I had purchased the Skinceuticals Lipid Restore for the 1st time and really appreciated how it performed. I was willing to purchase it again but after speaking with one of the excellent customer service agents at Dermluxe I wanted to give the Clinical skin replenishing Creme a trial. Surprisingly it works even better than the Skinceuticals especially when it comes to hydration and redness. If I need a little extra boost for my skin when it is winter I will add a few drops of a high quality facial oil to the Creme before applying it to my face. I am grateful for this product and the Retinol AOX renewal Creme. Thank you Dermluxe💐

Frequenty Asked Questions

Which skin types should use these products?

Our products are tested on all skin types. Results showed no evidence of irritation on any skin type.

Do I have to be a certain age to use this product?

This product and its benefits can be enjoyed by any person who would like to help prevent and improve the appearance of the signs of aging.

How long does it typically take to see results?

Clinical study participants experienced results of improved appearance of fine lines and skin firmness as early as four weeks. Individual results may vary.

Can you use this product while pregnant or breastfeeding?

We believe the safety of our customers is extremely important. We stand behind the safety and efficacy of our products. We do not conduct studies on pregnant women or nursing mothers, therefore we usually recommend customers speak to their physicians who know their medical history best.