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PolyPeptide Firming Serum

PolyPeptide Firming Serum

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Increases skin firmness and elasticity

Regular price $250.00 USD
Regular price Sale price $250.00 USD

Combat the signs of aging with 4 powerful peptides.
The award-winning Polypeptide Firming Serum’s science-backed formulation has multi-tasking peptides, antioxidants, ceramides and hyaluronic acid that will leave your skin feeling firmer and looking its best.


Size: 1.7 fl oz / 50 ml

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Minimizing wrinkles and a lifted appearance.

Clinically Proven to

FORTIFY: Increase skin firmness and elasticity to combat signs of aging

SUPPORT: Reduce the appearance of fine lines and wrinkles

MOISTURIZE: Improve skin moisture for a healthier appearance


- Fine lines

- Loss of Elasticity

- Loss of Firmness

- Wrinkles

- Decreased Hydration


- Delicate

- Non-Oily

- Quick Absorbing

Visible Results

- 97% reported more elasticity and a softer feel

- 74%* reported evened out skin tone

- 74%* reported less visible fine lines and wrinkles

IDEAL FOR: those who want younger, healthier looking skin while reducing the look of wrinkles and lines.

Key Ingredients


Copper Peptide
Bis (Tripeptide-1) Copper Acetate can help to support collagen and elastin, which can result in the reduction of fine lines, enlarged pores and signs of aging.
Acetyl Hexapeptide-8 works to help soften wrinkles while promoting a collagen-rich appearance to result in firmer looking skin.
Palmitoyl Tripeptide-38 is a protein fragment which works to help skin maintain its structure while minimizing uneven skin tone and dullness.
Palmitoyl Tripeptide-28
Palmitoyl Tripeptide-28 contributes to improvements in skin elasticity, firmness, and has soothing capabilities.

Supporting Ingredients

Hyaluronic Acid

All Ingredients

Water, Glycerin, Propanediol, Polyacrylate Crosspolymer-6, Tocopheryl Acetate, Acetyl Hexapeptide-8, Bis (Tripeptide-1) Copper Acetate, Palmitoyl Tripeptide-28, Palmitoyl Tripeptide-38, Ceramide AP, Ceramide EOP, Ceramide NP, Ceramide NG, Cholesterol, Phytosphingosine, Sodium Hyaluronate, Ascorbic Acid, Ergothioneine, Glutathione, Plankton Extract, Hydroxypropyl Cyclodextrin, Micrococcus Lysate, Xanthan Gum, Coco-Caprylate, Tetrasodium Glutamate Diacetate, Potassium Sorbate, Carbomer, Sodium Benzoate, Acetic Acid, Lecithin, Sodium Lauroyl Lactylate, Ethylhexylglycerin, Phenoxyethanol, Evodia Rutaecarpa Fruit Extract, Arabidopsis Thaliana Extract, Copper PCA, Zinc PCA, Kaolin

How to Apply

The PolyPeptide Firming Serum

Apply 7-10 drops of serum on freshly cleansed and dried skin
Gently massage into face, neck and décolleté, avoiding direct contact with the eyes
Repeat AM + PM
For external use only. If contact with eyes occurs, rinse thoroughly with water. Discontinue use if signs of irritation or rash appear. Keep out of reach of children.

Results Through Research.

Polypeptide Firming Serum is clinically proven* to show statistically significant improvements in the appearance of skin elasticity, fine lines, wrinkles and more.


improvement in skin firmness and elasticity


reduction in appearance of fine lines in just 3 months


improvement in moisturization

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*Results based on a U.S. based single-blinded 12-week clinical study of 35 subjects that applied Polypeptide Firming Serum twice daily. Data on file.

Clinical Study Participants Reported

Substantial Results

97%* More elasticity and a softer feel

94%* Overall improvement in skin’s appearance

84%* Healthier looking skin

94%* Overall improvement in skin’s appearance

74%* Less visible fine lines and wrinkles

*Percentage of subjects who reported improvement

Dermatologist Acclaimed

“Clinical Skin Polypeptide firming serum is the perfect blend of excellent ingredients with the right technology. It's able to deliver safe and effective results that have been shown in clinical studies, performing excellent as a maintenance program for my injectable and laser patients that want to maintain a medical skin grade skin care routine at home.

I endorse the product because it has been shown to reduce fine lines and improve skin texture as well as deliver firm skin in a very clean serum which is made for all skin types including sensitive skin.”

Dr Bertha Baum, Board-Certified Dermatologist

Dermatologist Acclaimed

"This multi-tasking treatment serum has become my “go to” for patients seeking the ultimate in skin firming and reduction in the appearance of fine lines and crepiness on the face, neck and decollate. Enhanced with copper peptide, Argireline and ceramides, its creamy, yet light serum consistency promotes a smooth and supple skin texture and serves as a key component of my patients’ home skincare regimen as well as a routine paring for my anti-aging in office procedures."

Dr. Lisa R Ginn, M.D., F.A.A.D. Board Certified Dermatologist Fellowship-trained Cosmetic Laser Surgeon

Customer Reviews

Based on 196 reviews
Carol Oconnor

Clinical Skin PolyPeptide Firming Serum

Stella Mora
Great serum

I’ve seen firmer and glowing skin. Superb serum.

Sara Van Dyke
Mixed feelings

I have been using the product for about 2 weeks and I like the results, but I don’t love it. To be honest, the packaging bothers me. It’s packaged in a small but heavy non translucent bottle. The bottle only holds 1.7 oz. I won’t be able to tell when I’m about to run out. Personally, I won’t spend this much money again for such a small amount of product, that is mostly expensive packaging.

Gwen Hamlin & Don Wilson

So far very happy with my Skin Essentials Anti-Aging collection that I got myself for Mother’s Day, pretty much everything I was feeling like I needed in one package. Wish it would come with a more detailed explanation of sequence and use of each item. Still haven’t figured out when to use the tiny bottle of Vitamin C Pro Collagen Serum!?

michele WYATT
Did not like

Did nothing but dry out skin

Frequenty Asked Questions

Which skin types should use these products?

Our products are tested on all skin types. Results showed no evidence of irritation on any skin type.

Do I have to be a certain age to use this product?

This product and its benefits can be enjoyed by any person who would like to help prevent and improve the appearance of the signs of aging.

How long does it typically take to see results?

Clinical study participants experienced results of improved appearance of fine lines and skin firmness as early as four weeks. Individual results may vary.

Can you use this product while pregnant or breastfeeding?

We believe the safety of our customers is extremely important. We stand behind the safety and efficacy of our products. We do not conduct studies on pregnant women or nursing mothers, therefore we usually recommend customers speak to their physicians who know their medical history best.